The cornerstone of control measures

The cornerstone of control measures attempting to prevent MDRO transmission is the uniform use of SP and hand hygiene,along with CP and appropriate environmental cleaning for specific
pathogens and situations, especially for outbreaks. When these practices are inadequate to control the spread of MDROs, a more intensive approach should be implemented. The combination
of a comprehensive infection control strategy and an effective antimicrobial stewardship program may be complementary and lead to the prevention of emergence and transmission of MDRO.
This includes multimodal strategies, variably combined, such as hand hygiene promotion, barrier precautions and asymptomatic patient decolonization, prevention bundles, environmental
decontamination and “high quality” antimicrobial prescription.To be potentially effective, such programs must be strongly supported by the hospital administration.