The body’s cells undergo two types

The body’s cells undergo two types of cell death: (1) unpro- grammed cell death due to cell injury, called necrosis, and (2) programmed cell death, called apoptosis. In both, mtDNA may initially be released from the organelle into the cytoplasm. The opening of the mitochondrial permeability transition pores of the inner membrane, the loss of mitochondrial outer membrane integrity,