Phitsanulok is a city growing economic, social, and political and is a major hub city in the region Lower North throughout many the past year with the expansion of the community and place of business. Road transport happen Tambon Plai Chumphon Muang, Phitsanulok. Dense with buildings, houses, shops. To meet the needs of the people. Result in a business area district Plai Chumphon by the business harmful to health. Defined by Article 31 of the Public Health Act 2535, which decreed that all 13 of the main business. Activities related to pets like pet breeding. Killing or slaughter of animals Business related to food, such as soft drinks, drinking water. Activities related to pharmaceuticals, medical devices, and cosmetics. Activities related to mineral or metal containers like jewelry, appliances or other equipment. business-related services, such as massage parlors hotel business business dormitory. Because the place of business of these may cause health effects on residents who live the vicinity. and workers in the workplace. If a deal cannot be controlled or sanitary systems. place of business that can cause air pollution, environmental impact and more. Hazardous waste, loud voice and so on.