ANTIARRHYTHMIC DRUGS
Antiarrhythmic drugs carry a significant risk of proarrhythmia along with other cardiovascular and noncardiovascular adverse effects (Table 1). Drugs with a
low therapeutic index, such as digoxin, or drugs
predominantly renally cleared, such as sotalol, should
be started at low doses. Although most cardiac drugs
can be used in the elderly, amiodarone and digoxin must
be used with caution and at low doses, and the planned
duration of therapy reassessed periodically