Similar results were reported by Co

Similar results were reported by Courraud et al. (2013) in carrot, but Granado-Lorencio et al. (2007) reported a higher carotenoid stability of about 70% in the final digesta of loquat, orange and broccoli. As mentioned before, these authors included the use of human pancreatic lipase, cholesterol esterase, phospholipase A2 and taurocholate salts during the intestinal digestion and also a previous homogenisation to simulate mastication and did not include a semipermeable membrane. In a different study, Granado et al. (2006) concluded that behaviour of carotenoids under in vitro gastrointestinal conditions does not fully explain changes observed in vivo, limiting the use of in vitro models for screening relative bioaccessibility of carotenoids.