P. americana and B. germanica can move stilly at night among hospital sections, patients’ places, and food-handling locations, mostly via cracks in walls, and their ability to transport of multidrug resistant infectious agents is a major concern for many health workers. In studies on isolated bacteria from hospital cockroaches, it has been shown that they could act as potential vectors of drug resistant bacteria[14]. They are potential to transmit some food-borne pathogens. They may thus spread some multidrug resistant bacteria at hospitals and food preparation and distribution centers. Antibiotics susceptibility of bacteria associated with hospital cockroaches thus possesses an increasingly significant challenge to health-associated systems.