Among levels did not correlate grou

Among levels did not correlate group, of the tested variables includ ing other with any antioxidants. This was in et al. (19) who studied group of chronically transfused we studied 43 patients with SCD O7 male, female) and 24 patients with TM(13 male and 11 female). They aged from 1.5 to 31.4 years and found that Levels of vitamin E as well as selenium were low and showed little association with iron overload, hemolysis, or SCD levels showed no correlations of serum ferritin and with any of the tested variables including other antioxidants. Many factors such as iron overload, liver injury. and hor monal disturbances affect lipids pattern among patients with major form of beta-thalassemi ia. Some authors suggested that accelerated erythropoiesis and increased uptake of LDL by macrophages and histiocytes of the reticuloendothelial system are the main determinants of low plasma cholesterol levels in beta thalassemia major[34.35] our data showed that total cholesterol and LDL-cholesterol, thalassemia group than as well as TG were significantly lower in relevant controls(P o.001) this was in agreement with the pre- vious reports 136.37. On the other hand, Chrysohoou et al. 135l halassemia patients. This is reported higher TG levels among t different from our results and can be explained by the younger age group included in our study. Similarly, SCD group had sig nificantly lower total cholesterol, LDLcholesterol, and TG unan controls(P 0.001), which is peculiar of this disease and this However, Total was in agreement with Vanderjagt et al. [38l cholesterol, LDL-cholesterol, as well as TG were within the nor mal range and were comparable in patients with beta tha lassemia and sickle cell anemia(P 0.05). In addition, there were no significant differences between mean HDL cholesterol levels in the three groups(P 0.05)