Finally, in coastal areas of anthropized estuaries such as the one analyzed in this study, whose management requires the knowledge of multiple factors, it is essential to include those that operate at large time scales, such as the ENSO phenomenon. This comprehensive analysis is crucial for the Rio de la Plata as it is a water source to more than 8 million people (Agua y Saneamiento Argentina, www.aysa.com.ar), and therefore a necessary requirement to manage this resource and implement mitigation measures according to the different environmental scenarios, ensuring the ecological integrity of the coastal ecosystem.