P. emblica and T. bellerica extracts
demonstrated growth inhibitory activity, with a certain
degree of selectivity against the two cancer cell lines
tested. Synergistic effects (CI < 1) for P. emblica /doxorubicin or cisplatin at different dose levels were
demonstrated in A549 and HepG2 cells. The T. bellerica /
cisplatin or doxorubicin also showed synergistic effects
in A549 and HepG2 cells. In some instances, the
combinations resulted in antagonistic effects. The
dose reduction level was different and specific to each
combination and cell line.