The calculated CPB was 176,000 QALYs saved over the lifetime of a birth cohort of
4,000,000, with a range in sensitivity analysis from 43% to 94% (primarily due to
variation in estimates of effectiveness). Screening and brief counseling was cost-saving from
the societal perspective and had a cost-effectiveness ratio of $1755/QALY saved from the
health-system perspective. Sensitivity analysis indicates that from both perspectives the
service is very cost effective and may be cost saving.