Male hypogonadism is defined as ‘in

Male hypogonadism is defined as ‘inadequate gonadal function, manifested by deficiency in gametogenesis and/or secretion of gonadal hormones’.1 It can be classified according to the site primarily involved in the hypothalamus-pituitary-gonadal axis. If the serum testosterone level is low and FSH and LH levels are elevated, the defect lies in the testis and hypergonadotropic hypogonadism is present. In these cases karyo type should be performed to rule out a chromosomal abnormality, such as Klinefelter’s syndrome (47, XXY; 46, XX; or 45, X/46, XY) which may occur in 10–15% of such patients. If testosterone is low and gonadotropins levels are low or normal, the patient has hypogonadotropic hypogonadism due to hypothalamic or pituitary disease.