Lasers and ultrasound machines are supercharging antioxidants in the derm’s office as well as at home. The effects of the gentle new Clear + Brilliant Permea fractionated laser are amplified with topical SkinCeuticals CE Ferulic serum, which, says Anne Chapas, MD, medical director of Union Square Laser Dermatology in New York City, makes it ideal for treating conditions such as melasma. “The laser makes your skin more permeable to topical skin care, so when an antioxidant is applied immediately after the treatment, that aids the removal of pigmentation and helps skin recover.” Similarly, at-home device JeNu bumps up the power of the brand’s proprietary topicals for eyes and lips by using ultrasound waves to propel 12 times more ingredients into skin than what penetrates through standard slathering. “It smooths and tightens,” Fusco says, “and diminishes the appearance of lines and wrinkles.”