Current evidence supports the positive association between the consumption of plant foods and health. In
this work, we assessed the effect of consuming a half-serving (30 g) or one serving (60 g) of broccoli
sprouts on the urinary concentrations of biomarkers of oxidative stress (isoprostanes) and inflammation
(prostaglandins and thromboxanes). Twenty-four volunteers participated in the project. A quantitative
determination of sulforaphane and its mercapturic derivatives, eicosanoids, and total vitamin C in urine
was performed. The intake of broccoli sprouts produced an increase in the urinary concentrations of
sulforaphane metabolites and vitamin C. Among the 13 eicosanoids analyzed, tetranor-PGEM and
11b-PGF2a as well as 11-dehydro-TXB2 showed a significant decrease in their urinary concentrations after
the ingestion of broccoli sprouts. Therefore, the consumption of broccoli sprouts modulated the excretion
of biomarkers linked to inflammation and vascular reactions without exerting a significant influence on
the oxidation of phospholipids in vivo.