The personal research study content

The personal research study contents in two aspects, one related to the determination of
particulate matter pollution in urban areas and one that evaluated evolution of of asthma in
a group of children treated with different classes of asthma medication. Clinical experiences
and dynamic tracking, through longitudinal studies of the development of asthma in
children have shown that therapeutic interventions in the early stages of the disease are
more effective. Also, a better knowledge and understanding of the pathogenic mechanisms
responsible for the onset and progression of the disease are needed to optimize asthma care.
The paper highlighted that air pollution can exacerbate asthma in pediatric patients
who have already condition and can also contribute to the initiation of new cases of asthma,
that from biological point of view is plausible in the light of current theories of
understanding of asthma as a complex disease with a variety of phenotypes.
This doctoral thesis focused on the objectives of asthma treatment in children for
decreased mortality and improvement of life quality. The specific addressed objectives of
the treatment are to reduce inflammation, improving lung function, reducing clinical
symptoms, reduce crises and therefore reduce hospitalizations, visits to emergency
departments, absences from school.