Figure 1. Visualization of binding

Figure 1. Visualization of binding modes within active sites of selected potential targets. All 16 ligands are shown in stick representation in the protein cavities of (a) CDK2 (pdb entry 1GII), (b) Aurora Kinase (pdb entry 2C6E) and (c) KIT (pdb entry 1T64). Substrates are represented as sticks, targets are shown either in a surface representation or as a ribbon with a binding pocket surface.