Two reviewauthors (XLY, BYW) independently assessed trial quality
based on the generation of the allocation sequence, allocation
concealment, blinding and follow-up. Finally, we assessed the risks
of bias as follows: A = low risk of bias (all of the criteria met);
B = moderate risk of bias (one or more criteria partly met); C =
high risk of bias (one or more criteria not met). Differences were
resolved by the arbitrator (BRD).
The detailed quality components were as follows