. A great value for formulation exp

. A great value for formulation expiration date is justified by the
absence of incompatibility with the excipients evaluated. The Ea (activation energy) was 89.4 kJ·mol-1
and 74.4 kJ·mol-1 for drug and for pharmaceutical formulation, respectively demonstrating their
stability. It can be observed in Table 7 that the degradation rate (k) is always higher in the
pharmaceutical formulation when compared to the drug, at each temperature isotherm.
t90 = (0,1 × Co)/k (3)
where k = rate constant (s-1), Co = initial concentration (%).