Use of nanomaterials or nanoparticl

Use of nanomaterials or nanoparticles in biosensors allows the use of many new signal transduction technologies.

Many biosensors based on nanotechnology for the molecular detection of foodborne pathogens and bio-terrorism agents can be found in the literature.

These detection techniques include conductive polymer nanowires (Pal et al., 2008), nano-porous silicon (Mathew and Alocilja, 2005; Zhang and Alocilja, 2008), gold nanoparticles
(Li et al., 2009; Wang et al., 2010) and carbon nanotubes (Poonam and Deo, 2008).


Three nanoparticle tracers (NTs) have been used to differentiate the signal of three DNA targets in connection with a sandwich hybridization assay and stripping voltammetry of the corresponding heavy metals (Wang et al.,2003).

A bio-barcodedDNAassay utilizes oligonucleotide-modified gold nanoparticles (AuNPs) for signal amplification and magnetic nanoparticles (MNPs) for easy separation from the sample.