This short communication aims at de

This short communication aims at developing a thermostatted kinetic framework which includes conservative and nonconservative interactions. Specifically nonconservative interactions refer to proliferative/destructive and mutative events. The thermostatted kinetic framework is a set of autonomous partial integro-differential equations with quadratic nonlinearity. How the moments evolution is modified by mutative interactions is explored in the present communication. Applications refer to the cancer-immune system competition. © 2013 Elsevier B.V.