Before UsingIn deciding to use a me

Before Using

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of azilsartan and chlorthalidone combination in the pediatric population. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of azilsartan and chlorthalidone combination in the elderly.

Pregnancy

Pregnancy Category Explanation
All Trimesters D Studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy in a life threatening situation or a serious disease, may outweigh the potential risk.
Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Drug Interactions

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Acetyldigoxin
Arsenic Trioxide
Benazepril
Bepridil
Deslanoside
Digitalis
Digitoxin
Digoxin
Dofetilide
Droperidol
Enalapril
Enalaprilat
Flecainide
Ketanserin
Levomethadyl
Lisinopril
Lithium
Metildigoxin
Moexipril
Perindopril
Quinapril
Ramipril
Sotalol
Trandolapril
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Alacepril
Apazone
Aspirin
Benazepril
Bromfenac
Captopril
Celecoxib
Chlorpropamide
Cilazapril
Delapril
Diclofenac
Diflunisal
Enalaprilat
Enalapril Maleate
Etodolac
Fenoprofen
Flurbiprofen
Fosinopril
Gossypol
Ibuprofen
Ibuprofen Lysine
Imidapril
Indomethacin
Ketoprofen
Ketorolac
Licorice
Lisinopril
Magnesium Salicylate
Meclofenamate
Mefenamic Acid
Meloxicam
Moexipril
Nabumetone
Naproxen
Nepafenac
Oxaprozin
Pentopril
Perindopril
Piroxicam
Quinapril
Ramipril
Salicylic Acid
Salsalate
Spirapril
Sulindac
Temocapril
Tolmetin
Trandolapril
Zofenopril
Other Interactions

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

Anuria (not able to pass urine) or
Diabetic patients who are also taking aliskiren (Tekturna®)—Should not be used in patients with these conditions.
Congestive heart failure, severe—Use may lead to kidney problems.
Electrolyte imbalances (e.g., low potassium or sodium in the body) or
Fluid imbalances (caused by dehydration, vomiting, or diarrhea) or
Gout or
Kidney problems or
Liver disease—Use with caution. May make these conditions worse.